Predicting cell-to-cell communication networks using NATMI

Single cell expression data allows for inferring cell-cell communication between cells expressing ligands and those expressing their cognate receptors. Here the authors present an updated and curated database of ligand-receptor pairs and a Python-based toolkit to construct and analyse communication...

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Autores principales: Rui Hou, Elena Denisenko, Huan Ting Ong, Jordan A. Ramilowski, Alistair R. R. Forrest
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/13c6a71b877344e9a02d65c79002e3c6
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Sumario:Single cell expression data allows for inferring cell-cell communication between cells expressing ligands and those expressing their cognate receptors. Here the authors present an updated and curated database of ligand-receptor pairs and a Python-based toolkit to construct and analyse communication networks from single cell and bulk expression data.