Modulation of Cellular NAD<sup>+</sup> Attenuates Cancer-Associated Hypercoagulability and Thrombosis via the Inhibition of Tissue Factor and Formation of Neutrophil Extracellular Traps
Cancer-associated thrombosis is the second-leading cause of mortality in patients with cancer and presents a poor prognosis, with a lack of effective treatment strategies. NAD(P)H quinone oxidoreductase 1 (NQO1) increases the cellular nicotinamide adenine dinucleotide (NAD<sup>+</sup>) l...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
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MDPI AG
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/13c7afa97e9841b28f1e57e3c3b7e482 |
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