Transcriptional overlap links DNA hypomethylation with DNA hypermethylation at adjacent promoters in cancer

Abstract Tumor development involves alterations in DNA methylation patterns, which include both gains (hypermethylation) and losses (hypomethylation) in different genomic regions. The mechanisms underlying these two opposite, yet co-existing, alterations in tumors remain unclear. While studying the...

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Autores principales: Jean S. Fain, Axelle Loriot, Anna Diacofotaki, Aurélie Van Tongelen, Charles De Smet
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/13c815e52ba34a6ab5ae1ab31236669e
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