Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection

Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection

Abstract The global coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive-sense RNA virus. How the host immune system senses and responds to SARS-CoV-2 infection remain largely unresolved. Here, we report that SARS-CoV-2 in...

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Autores principales: Zhuo Zhou, Xinyi Zhang, Xiaobo Lei, Xia Xiao, Tao Jiao, Ruiyi Ma, Xiaojing Dong, Qi Jiang, Wenjing Wang, Yujin Shi, Tian Zheng, Jian Rao, Zichun Xiang, Lili Ren, Tao Deng, Zhengfan Jiang, Zhixun Dou, Wensheng Wei, Jianwei Wang
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Medicine
R
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/13cb6a7b4ff242b7bbd1dc4b4373cfb3
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