Splenectomy is associated with sexual dysfunctions and decreased libido

Abstract The removal of the spleen due to disease or trauma may be followed by disorders due to the asplenism, including immunodeficiency, hematological and metabolic diseases, mainly dyslipidemia, which can lead to sepsis, pulmonary embolism and early death. Although patients frequently report sexu...

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Autores principales: Kelly Renata Sabino, Andy Petroianu
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/13cd79b474c34dc78eb4be5d3f6513e9
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spelling oai:doaj.org-article:13cd79b474c34dc78eb4be5d3f6513e92021-11-08T10:52:48ZSplenectomy is associated with sexual dysfunctions and decreased libido10.1038/s41598-021-01371-72045-2322https://doaj.org/article/13cd79b474c34dc78eb4be5d3f6513e92021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01371-7https://doaj.org/toc/2045-2322Abstract The removal of the spleen due to disease or trauma may be followed by disorders due to the asplenism, including immunodeficiency, hematological and metabolic diseases, mainly dyslipidemia, which can lead to sepsis, pulmonary embolism and early death. Although patients frequently report sexual disinterest after splenectomy, this feature has been experimentally studied only in a translational investigation performed by the same group of this work. To study libido and other sexual functions after the complete removal of the spleen in humans. This study was performed on 60 healthy adults, 30 men and 30 women, after more than 1 year of total splenectomy to treat isolated splenic trauma. The International Index of Erectile Function was applied to men and the Female Sexual Function Index to women. The analysis compared the responses obtained in the periods before and after the splenectomy. Laboratory tests with hematological and biochemical analyses, including sex hormones, were performed in all patients. The pre- and postoperative results were compared in each group using the paired t-test, with each patient being his or her own control and with significance to p < 0.05. A decrease in libido and an increase in sexual dysfunction was observed after splenectomy in all men and women, p < 0.001. All postoperative laboratory tests showed normal values in both genders. Asplenia is associated with a marked decrease in libido and intense sexual dysfunction in both men and women, with normal hematological and biochemical laboratory tests, including hormonal exams.Kelly Renata SabinoAndy PetroianuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Kelly Renata Sabino
Andy Petroianu
Splenectomy is associated with sexual dysfunctions and decreased libido
description Abstract The removal of the spleen due to disease or trauma may be followed by disorders due to the asplenism, including immunodeficiency, hematological and metabolic diseases, mainly dyslipidemia, which can lead to sepsis, pulmonary embolism and early death. Although patients frequently report sexual disinterest after splenectomy, this feature has been experimentally studied only in a translational investigation performed by the same group of this work. To study libido and other sexual functions after the complete removal of the spleen in humans. This study was performed on 60 healthy adults, 30 men and 30 women, after more than 1 year of total splenectomy to treat isolated splenic trauma. The International Index of Erectile Function was applied to men and the Female Sexual Function Index to women. The analysis compared the responses obtained in the periods before and after the splenectomy. Laboratory tests with hematological and biochemical analyses, including sex hormones, were performed in all patients. The pre- and postoperative results were compared in each group using the paired t-test, with each patient being his or her own control and with significance to p < 0.05. A decrease in libido and an increase in sexual dysfunction was observed after splenectomy in all men and women, p < 0.001. All postoperative laboratory tests showed normal values in both genders. Asplenia is associated with a marked decrease in libido and intense sexual dysfunction in both men and women, with normal hematological and biochemical laboratory tests, including hormonal exams.
format article
author Kelly Renata Sabino
Andy Petroianu
author_facet Kelly Renata Sabino
Andy Petroianu
author_sort Kelly Renata Sabino
title Splenectomy is associated with sexual dysfunctions and decreased libido
title_short Splenectomy is associated with sexual dysfunctions and decreased libido
title_full Splenectomy is associated with sexual dysfunctions and decreased libido
title_fullStr Splenectomy is associated with sexual dysfunctions and decreased libido
title_full_unstemmed Splenectomy is associated with sexual dysfunctions and decreased libido
title_sort splenectomy is associated with sexual dysfunctions and decreased libido
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/13cd79b474c34dc78eb4be5d3f6513e9
work_keys_str_mv AT kellyrenatasabino splenectomyisassociatedwithsexualdysfunctionsanddecreasedlibido
AT andypetroianu splenectomyisassociatedwithsexualdysfunctionsanddecreasedlibido
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