Histological and immunohistochemical characteristics of brain meningiomas

Meningiomas are among the most common primary intracranial tumors. They arise from meningothelial cells of the arachnoid layer that forms the external lining of the brain and occur primarily at the base of the skull in the parasellar regions as well as over the cerebral convexities. Of particular di...

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Autores principales:	V. A. Byvaltsev, V. A. Sorokovikov, I. A. Stepanov, S. L. Antipina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	meningioma benign typical anaplastic immunohistochemistry markers Science Q
Acceso en línea:	https://doaj.org/article/13d82f966e7d42ae923978f79fe8bfd6
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id	oai:doaj.org-article:13d82f966e7d42ae923978f79fe8bfd6
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spelling	oai:doaj.org-article:13d82f966e7d42ae923978f79fe8bfd62021-11-23T06:14:35ZHistological and immunohistochemical characteristics of brain meningiomas2541-94202587-959610.12737/23031https://doaj.org/article/13d82f966e7d42ae923978f79fe8bfd62016-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/266https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Meningiomas are among the most common primary intracranial tumors. They arise from meningothelial cells of the arachnoid layer that forms the external lining of the brain and occur primarily at the base of the skull in the parasellar regions as well as over the cerebral convexities. Of particular difficulty are anaplastic meningiomas, having similarities with malignant soft tissue tumors. Immunostaining allows to define not only the source of cytogenetic, tumor grade, but detect abnormal proteins - transcription products damaged DNA regions and make recommendations for the appointment of targeted therapy. Targeted effect on the meningioma will allow to achieve a significant increase in patient survival.V. A. ByvaltsevV. A. SorokovikovI. A. StepanovS. L. AntipinaScientific Сentre for Family Health and Human Reproduction ProblemsarticlemeningiomabenigntypicaltypicalanaplasticimmunohistochemistrymarkersScienceQRUActa Biomedica Scientifica, Vol 1, Iss 4, Pp 187-194 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	meningioma benign typical typical anaplastic immunohistochemistry markers Science Q
spellingShingle	meningioma benign typical typical anaplastic immunohistochemistry markers Science Q V. A. Byvaltsev V. A. Sorokovikov I. A. Stepanov S. L. Antipina Histological and immunohistochemical characteristics of brain meningiomas
description	Meningiomas are among the most common primary intracranial tumors. They arise from meningothelial cells of the arachnoid layer that forms the external lining of the brain and occur primarily at the base of the skull in the parasellar regions as well as over the cerebral convexities. Of particular difficulty are anaplastic meningiomas, having similarities with malignant soft tissue tumors. Immunostaining allows to define not only the source of cytogenetic, tumor grade, but detect abnormal proteins - transcription products damaged DNA regions and make recommendations for the appointment of targeted therapy. Targeted effect on the meningioma will allow to achieve a significant increase in patient survival.
format	article
author	V. A. Byvaltsev V. A. Sorokovikov I. A. Stepanov S. L. Antipina
author_facet	V. A. Byvaltsev V. A. Sorokovikov I. A. Stepanov S. L. Antipina
author_sort	V. A. Byvaltsev
title	Histological and immunohistochemical characteristics of brain meningiomas
title_short	Histological and immunohistochemical characteristics of brain meningiomas
title_full	Histological and immunohistochemical characteristics of brain meningiomas
title_fullStr	Histological and immunohistochemical characteristics of brain meningiomas
title_full_unstemmed	Histological and immunohistochemical characteristics of brain meningiomas
title_sort	histological and immunohistochemical characteristics of brain meningiomas
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/13d82f966e7d42ae923978f79fe8bfd6
work_keys_str_mv	AT vabyvaltsev histologicalandimmunohistochemicalcharacteristicsofbrainmeningiomas AT vasorokovikov histologicalandimmunohistochemicalcharacteristicsofbrainmeningiomas AT iastepanov histologicalandimmunohistochemicalcharacteristicsofbrainmeningiomas AT slantipina histologicalandimmunohistochemicalcharacteristicsofbrainmeningiomas
_version_	1718417052813754368

Histological and immunohistochemical characteristics of brain meningiomas

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