Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner

Dietary restriction (DR) can increase protein persulfidation but the tissue specificity of this process is not well understood. Here, the authors compare organ-specific protein persulfidomes in young and aged mice under DR, and show that DR-dependent persulfidome changes depend on cystathionine γ-ly...

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Autores principales:	Nazmin Bithi, Christopher Link, Yoko O. Henderson, Suzie Kim, Jie Yang, Ling Li, Rui Wang, Belinda Willard, Christopher Hine
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/13e578f4e45e44eaaf178261c972e2ba
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spelling	oai:doaj.org-article:13e578f4e45e44eaaf178261c972e2ba2021-12-02T17:04:52ZDietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner10.1038/s41467-021-22001-w2041-1723https://doaj.org/article/13e578f4e45e44eaaf178261c972e2ba2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22001-whttps://doaj.org/toc/2041-1723Dietary restriction (DR) can increase protein persulfidation but the tissue specificity of this process is not well understood. Here, the authors compare organ-specific protein persulfidomes in young and aged mice under DR, and show that DR-dependent persulfidome changes depend on cystathionine γ-lyase.Nazmin BithiChristopher LinkYoko O. HendersonSuzie KimJie YangLing LiRui WangBelinda WillardChristopher HineNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nazmin Bithi Christopher Link Yoko O. Henderson Suzie Kim Jie Yang Ling Li Rui Wang Belinda Willard Christopher Hine Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner
description	Dietary restriction (DR) can increase protein persulfidation but the tissue specificity of this process is not well understood. Here, the authors compare organ-specific protein persulfidomes in young and aged mice under DR, and show that DR-dependent persulfidome changes depend on cystathionine γ-lyase.
format	article
author	Nazmin Bithi Christopher Link Yoko O. Henderson Suzie Kim Jie Yang Ling Li Rui Wang Belinda Willard Christopher Hine
author_facet	Nazmin Bithi Christopher Link Yoko O. Henderson Suzie Kim Jie Yang Ling Li Rui Wang Belinda Willard Christopher Hine
author_sort	Nazmin Bithi
title	Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner
title_short	Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner
title_full	Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner
title_fullStr	Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner
title_full_unstemmed	Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner
title_sort	dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/13e578f4e45e44eaaf178261c972e2ba
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Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner

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