Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA

The HIV-1 RNA-binding protein rev facilitates nuclear export of viral RNA. Here, the authors use native mass spectrometry to study the interactions between rev-derived peptides and rev response elements of HIV-1 RNA, providing mechanistic insights into rev recognition and recruitment.

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Autores principales:	Eva-Maria Schneeberger, Matthias Halper, Michael Palasser, Sarah Viola Heel, Jovana Vušurović, Raphael Plangger, Michael Juen, Christoph Kreutz, Kathrin Breuker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/13e70d04a2b44c299060a0fd63802d9e
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spelling	oai:doaj.org-article:13e70d04a2b44c299060a0fd63802d9e2021-12-02T15:39:28ZNative mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA10.1038/s41467-020-19144-72041-1723https://doaj.org/article/13e70d04a2b44c299060a0fd63802d9e2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19144-7https://doaj.org/toc/2041-1723The HIV-1 RNA-binding protein rev facilitates nuclear export of viral RNA. Here, the authors use native mass spectrometry to study the interactions between rev-derived peptides and rev response elements of HIV-1 RNA, providing mechanistic insights into rev recognition and recruitment.Eva-Maria SchneebergerMatthias HalperMichael PalasserSarah Viola HeelJovana VušurovićRaphael PlanggerMichael JuenChristoph KreutzKathrin BreukerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eva-Maria Schneeberger Matthias Halper Michael Palasser Sarah Viola Heel Jovana Vušurović Raphael Plangger Michael Juen Christoph Kreutz Kathrin Breuker Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
description	The HIV-1 RNA-binding protein rev facilitates nuclear export of viral RNA. Here, the authors use native mass spectrometry to study the interactions between rev-derived peptides and rev response elements of HIV-1 RNA, providing mechanistic insights into rev recognition and recruitment.
format	article
author	Eva-Maria Schneeberger Matthias Halper Michael Palasser Sarah Viola Heel Jovana Vušurović Raphael Plangger Michael Juen Christoph Kreutz Kathrin Breuker
author_facet	Eva-Maria Schneeberger Matthias Halper Michael Palasser Sarah Viola Heel Jovana Vušurović Raphael Plangger Michael Juen Christoph Kreutz Kathrin Breuker
author_sort	Eva-Maria Schneeberger
title	Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
title_short	Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
title_full	Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
title_fullStr	Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
title_full_unstemmed	Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
title_sort	native mass spectrometry reveals the initial binding events of hiv-1 rev to rre stem ii rna
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/13e70d04a2b44c299060a0fd63802d9e
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Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA

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