Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
The HIV-1 RNA-binding protein rev facilitates nuclear export of viral RNA. Here, the authors use native mass spectrometry to study the interactions between rev-derived peptides and rev response elements of HIV-1 RNA, providing mechanistic insights into rev recognition and recruitment.
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Main Authors: | Eva-Maria Schneeberger, Matthias Halper, Michael Palasser, Sarah Viola Heel, Jovana Vušurović, Raphael Plangger, Michael Juen, Christoph Kreutz, Kathrin Breuker |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/13e70d04a2b44c299060a0fd63802d9e |
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