Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.

Knowledge on prescribed medication is important for medication adherence. We determined the presence of cognitive impairment in neurological patients who report not to know reasons and dosages of their medication. Data from 350 patients were collected: sociodemographic data, German Stendal Adherence...

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Autores principales:	Hannah M Zipprich, Tino Prell
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/13ee10319e124729bfd2c8f923464fa3
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spelling	oai:doaj.org-article:13ee10319e124729bfd2c8f923464fa32021-12-02T20:05:35ZDifficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.1932-620310.1371/journal.pone.0251374https://doaj.org/article/13ee10319e124729bfd2c8f923464fa32021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0251374https://doaj.org/toc/1932-6203Knowledge on prescribed medication is important for medication adherence. We determined the presence of cognitive impairment in neurological patients who report not to know reasons and dosages of their medication. Data from 350 patients were collected: sociodemographic data, German Stendal Adherence to Medication Score (SAMS), Montreal Cognitive Assessment (MoCA), and Beck Depression Inventory-II (BDI-II). Eighty-eight (29.0%) patients did not know the reasons for taking their prescribed medication and 83 (27.4%) did not know the doses. Sixty-three (20.8%) knew neither reasons nor dosage. The latter were characterized by higher nonadherence, higher number of prescribed medication per day, lower MoCA, higher BDI, and had more often a lower education level compared with patients who knew the reasons. The MANOVA revealed a significant multivariate effect for not knowing the reasons and not knowing the dosages of medication on MoCA and BDI. Significant univariate effects for not knowing reasons were found for depressive mood, but not for cognitive performance. Significant univariate effects for not knowing dosages were found for cognitive performance, but not for depressive mood. Inaccurate medication reporting is not solely associated with cognitive problems, but also with depression, which has to be taken into account in daily practice and research.Hannah M ZipprichTino PrellPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 5, p e0251374 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hannah M Zipprich Tino Prell Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.
description	Knowledge on prescribed medication is important for medication adherence. We determined the presence of cognitive impairment in neurological patients who report not to know reasons and dosages of their medication. Data from 350 patients were collected: sociodemographic data, German Stendal Adherence to Medication Score (SAMS), Montreal Cognitive Assessment (MoCA), and Beck Depression Inventory-II (BDI-II). Eighty-eight (29.0%) patients did not know the reasons for taking their prescribed medication and 83 (27.4%) did not know the doses. Sixty-three (20.8%) knew neither reasons nor dosage. The latter were characterized by higher nonadherence, higher number of prescribed medication per day, lower MoCA, higher BDI, and had more often a lower education level compared with patients who knew the reasons. The MANOVA revealed a significant multivariate effect for not knowing the reasons and not knowing the dosages of medication on MoCA and BDI. Significant univariate effects for not knowing reasons were found for depressive mood, but not for cognitive performance. Significant univariate effects for not knowing dosages were found for cognitive performance, but not for depressive mood. Inaccurate medication reporting is not solely associated with cognitive problems, but also with depression, which has to be taken into account in daily practice and research.
format	article
author	Hannah M Zipprich Tino Prell
author_facet	Hannah M Zipprich Tino Prell
author_sort	Hannah M Zipprich
title	Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.
title_short	Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.
title_full	Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.
title_fullStr	Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.
title_full_unstemmed	Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.
title_sort	difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/13ee10319e124729bfd2c8f923464fa3
work_keys_str_mv	AT hannahmzipprich difficultiesinreportingpurposeanddosageofprescribedmedicationsareassociatedwithpoorcognitionanddepression AT tinoprell difficultiesinreportingpurposeanddosageofprescribedmedicationsareassociatedwithpoorcognitionanddepression
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Difficulties in reporting purpose and dosage of prescribed medications are associated with poor cognition and depression.

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