Alternative transcription cycle for bacterial RNA polymerase

In the canonical bacterial transcription, both nascent transcript and polymerase dissociate from template DNA. By employing multi-color single-molecule fluorescence imaging, here the authors show that RNA polymerases remain bound to DNA after the transcript release.

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Autores principales:	Timothy T. Harden, Karina S. Herlambang, Mathew Chamberlain, Jean-Benoît Lalanne, Christopher D. Wells, Gene-Wei Li, Robert Landick, Ann Hochschild, Jane Kondev, Jeff Gelles
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/13f680680f904593b7b3498bafa4968b
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spelling	oai:doaj.org-article:13f680680f904593b7b3498bafa4968b2021-12-02T15:39:11ZAlternative transcription cycle for bacterial RNA polymerase10.1038/s41467-019-14208-92041-1723https://doaj.org/article/13f680680f904593b7b3498bafa4968b2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14208-9https://doaj.org/toc/2041-1723In the canonical bacterial transcription, both nascent transcript and polymerase dissociate from template DNA. By employing multi-color single-molecule fluorescence imaging, here the authors show that RNA polymerases remain bound to DNA after the transcript release.Timothy T. HardenKarina S. HerlambangMathew ChamberlainJean-Benoît LalanneChristopher D. WellsGene-Wei LiRobert LandickAnn HochschildJane KondevJeff GellesNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothy T. Harden Karina S. Herlambang Mathew Chamberlain Jean-Benoît Lalanne Christopher D. Wells Gene-Wei Li Robert Landick Ann Hochschild Jane Kondev Jeff Gelles Alternative transcription cycle for bacterial RNA polymerase
description	In the canonical bacterial transcription, both nascent transcript and polymerase dissociate from template DNA. By employing multi-color single-molecule fluorescence imaging, here the authors show that RNA polymerases remain bound to DNA after the transcript release.
format	article
author	Timothy T. Harden Karina S. Herlambang Mathew Chamberlain Jean-Benoît Lalanne Christopher D. Wells Gene-Wei Li Robert Landick Ann Hochschild Jane Kondev Jeff Gelles
author_facet	Timothy T. Harden Karina S. Herlambang Mathew Chamberlain Jean-Benoît Lalanne Christopher D. Wells Gene-Wei Li Robert Landick Ann Hochschild Jane Kondev Jeff Gelles
author_sort	Timothy T. Harden
title	Alternative transcription cycle for bacterial RNA polymerase
title_short	Alternative transcription cycle for bacterial RNA polymerase
title_full	Alternative transcription cycle for bacterial RNA polymerase
title_fullStr	Alternative transcription cycle for bacterial RNA polymerase
title_full_unstemmed	Alternative transcription cycle for bacterial RNA polymerase
title_sort	alternative transcription cycle for bacterial rna polymerase
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/13f680680f904593b7b3498bafa4968b
work_keys_str_mv	AT timothytharden alternativetranscriptioncycleforbacterialrnapolymerase AT karinasherlambang alternativetranscriptioncycleforbacterialrnapolymerase AT mathewchamberlain alternativetranscriptioncycleforbacterialrnapolymerase AT jeanbenoitlalanne alternativetranscriptioncycleforbacterialrnapolymerase AT christopherdwells alternativetranscriptioncycleforbacterialrnapolymerase AT geneweili alternativetranscriptioncycleforbacterialrnapolymerase AT robertlandick alternativetranscriptioncycleforbacterialrnapolymerase AT annhochschild alternativetranscriptioncycleforbacterialrnapolymerase AT janekondev alternativetranscriptioncycleforbacterialrnapolymerase AT jeffgelles alternativetranscriptioncycleforbacterialrnapolymerase
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Alternative transcription cycle for bacterial RNA polymerase

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