EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
Interleukin 9 (IL-9) producing helper T cells (Th) have established roles in a range of inflammatory conditions and a number of transcription factors have been shown crucial for the generation of these IL-9 producing cells. Here, the authors establish a role for the EGFR-HIF1α axis in the regulation...
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| Autores principales: | , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/14041d28e0bb45c4a04d8f9ed2052668 |
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| Sumario: | Interleukin 9 (IL-9) producing helper T cells (Th) have established roles in a range of inflammatory conditions and a number of transcription factors have been shown crucial for the generation of these IL-9 producing cells. Here, the authors establish a role for the EGFR-HIF1α axis in the regulation of IL-9 producing Th cell populations. |
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