EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

Interleukin 9 (IL-9) producing helper T cells (Th) have established roles in a range of inflammatory conditions and a number of transcription factors have been shown crucial for the generation of these IL-9 producing cells. Here, the authors establish a role for the EGFR-HIF1α axis in the regulation...

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Autores principales:	Suyasha Roy, Zaigham Abbas Rizvi, Alexander J. Clarke, Felicity Macdonald, Abhaydeep Pandey, Dietmar Martin Werner Zaiss, Anna Kathrina Simon, Amit Awasthi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/14041d28e0bb45c4a04d8f9ed2052668
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spelling	oai:doaj.org-article:14041d28e0bb45c4a04d8f9ed20526682021-12-02T15:02:55ZEGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells10.1038/s41467-021-23042-x2041-1723https://doaj.org/article/14041d28e0bb45c4a04d8f9ed20526682021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23042-xhttps://doaj.org/toc/2041-1723Interleukin 9 (IL-9) producing helper T cells (Th) have established roles in a range of inflammatory conditions and a number of transcription factors have been shown crucial for the generation of these IL-9 producing cells. Here, the authors establish a role for the EGFR-HIF1α axis in the regulation of IL-9 producing Th cell populations.Suyasha RoyZaigham Abbas RizviAlexander J. ClarkeFelicity MacdonaldAbhaydeep PandeyDietmar Martin Werner ZaissAnna Kathrina SimonAmit AwasthiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Suyasha Roy Zaigham Abbas Rizvi Alexander J. Clarke Felicity Macdonald Abhaydeep Pandey Dietmar Martin Werner Zaiss Anna Kathrina Simon Amit Awasthi EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
description	Interleukin 9 (IL-9) producing helper T cells (Th) have established roles in a range of inflammatory conditions and a number of transcription factors have been shown crucial for the generation of these IL-9 producing cells. Here, the authors establish a role for the EGFR-HIF1α axis in the regulation of IL-9 producing Th cell populations.
format	article
author	Suyasha Roy Zaigham Abbas Rizvi Alexander J. Clarke Felicity Macdonald Abhaydeep Pandey Dietmar Martin Werner Zaiss Anna Kathrina Simon Amit Awasthi
author_facet	Suyasha Roy Zaigham Abbas Rizvi Alexander J. Clarke Felicity Macdonald Abhaydeep Pandey Dietmar Martin Werner Zaiss Anna Kathrina Simon Amit Awasthi
author_sort	Suyasha Roy
title	EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
title_short	EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
title_full	EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
title_fullStr	EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
title_full_unstemmed	EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
title_sort	egfr-hif1α signaling positively regulates the differentiation of il-9 producing t helper cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/14041d28e0bb45c4a04d8f9ed2052668
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EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

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