EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

Interleukin 9 (IL-9) producing helper T cells (Th) have established roles in a range of inflammatory conditions and a number of transcription factors have been shown crucial for the generation of these IL-9 producing cells. Here, the authors establish a role for the EGFR-HIF1α axis in the regulation...

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Autores principales: Suyasha Roy, Zaigham Abbas Rizvi, Alexander J. Clarke, Felicity Macdonald, Abhaydeep Pandey, Dietmar Martin Werner Zaiss, Anna Kathrina Simon, Amit Awasthi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/14041d28e0bb45c4a04d8f9ed2052668
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