A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in <italic toggle="yes">Aspergillus fumigatus</italic>

A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in <italic toggle="yes">Aspergillus fumigatus</italic>

ABSTRACT Invasive aspergillosis (IA), caused by the filamentous fungal pathogen Aspergillus fumigatus, is a major cause of death among immunocompromised patients. The cyclic AMP/protein kinase A (PKA) signaling pathway is essential for hyphal growth and virulence of A. fumigatus, but the mechanism o...

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Autores principales: E. Keats Shwab, Praveen R. Juvvadi, Greg Waitt, Erik J. Soderblom, M. Arthur Moseley, Nathan I. Nicely, Yohannes G. Asfaw, William J. Steinbach
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/140506a1f19b4a60a82b864e85bf4afe
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