HMMerThread: detecting remote, functional conserved domains in entire genomes by combining relaxed sequence-database searches with fold recognition.

Conserved domains in proteins are one of the major sources of functional information for experimental design and genome-level annotation. Though search tools for conserved domain databases such as Hidden Markov Models (HMMs) are sensitive in detecting conserved domains in proteins when they share su...

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Bibliographic Details
Main Authors: Charles Richard Bradshaw, Vineeth Surendranath, Robert Henschel, Matthias Stefan Mueller, Bianca Hermine Habermann
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/141019c298e24b82a0f5faed12963047
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