Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness

Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness

Kelechi C Ogbuehi, Uchechukwu L OsuagwuOutpatient Clinic, Department of Optometry, King Saud University, Riyadh, Kingdom of Saudi ArabiaBackground: The purpose of this study was to assess the repeatability and limits of agreement of corneal thickness values measured by a high-frequency ultrasound (A...

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Autores principales: Ogbuehi KC, Osuagwu UL
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2012
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Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/1415c67b314e48ba944d3d7e9bbbe862
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spelling oai:doaj.org-article:1415c67b314e48ba944d3d7e9bbbe8622021-12-02T09:59:16ZRepeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness1177-54671177-5483https://doaj.org/article/1415c67b314e48ba944d3d7e9bbbe8622012-05-01T00:00:00Zhttp://www.dovepress.com/repeatability-and-interobserver-reproducibility-of-artemis-2-high-freq-a9936https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kelechi C Ogbuehi, Uchechukwu L OsuagwuOutpatient Clinic, Department of Optometry, King Saud University, Riyadh, Kingdom of Saudi ArabiaBackground: The purpose of this study was to assess the repeatability and limits of agreement of corneal thickness values measured by a high-frequency ultrasound (Artemis-2), hand-held ultrasound pachymeter (DGH-500) and a specular microscope (SP-3000P).Methods: Central corneal thickness (CCT) was analyzed in this prospective randomized study that included 32 patients (18 men and 14 women) aged 21–24 years. Measurements were obtained in two sessions, one week apart, by two examiners with three devices in a randomized order. Nine measurements were taken (three with each device) on one randomly selected eye of each patient in each measurement session. The coefficient of repeatability and interobserver reproducibility for the values of each method were calculated. The limits of agreement between techniques were also evaluated.Results: There were no significant differences in CCT values between sessions for each of the three devices (P > 0.05). The repeatability coefficients for the Artemis-2 (±8 µm/±9 µm) were superior to those of the SP-3000P (±9 µm/±11 µm) and DGH 500 (±12 µm/±12 µm) in session 1/session 2 respectively, while the interobserver reproducibility index (differences between session 1 and session 2) was superior for the SP-3000P (±17 µm) with respect to DHG-500 (±29 µm) and the Artemis-2 (±31 µm). In session 1 and session 2, the limits of agreement between the techniques were 35 µm to -31 µm and 34 to -20 µm, respectively, for DGH-500 versus Artemis-2, 73 µm to 3 µm and 60 µm to 9 µm for Artemis-2 versus SP-3000P, and 58 µm to 22 µm and 72 µm to 10 µm for DGH-500 versus SP-3000P comparisons. The DGH-500 and Artemis-2 gave similar values (P > 0.05) in both sessions, but both (Artemis-2 and DGH-500) values were significantly greater than that of the SP-3000P (P < 0.05) in both sessions.Conclusion: Repeatability was comparably good for the three techniques. However, interobserver reproducibility was approximately twice as good with the SP-3000P compared with the other two devices. The Artemis-2 CCT values consistently agreed with the DGH-500 and less so with the SP-3000P. The Artemis-2 provided CCT values that were, on average, 38 µm and 34 µm greater than that of the SP-3000P in session 1 and session 2, respectively.Keywords: cornea thickness, Artemis-2 ultrasound, hand-held ultrasound, SP-3000P noncontact specular microscopy, reproducibilityOgbuehi KCOsuagwu ULDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 761-769 (2012)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Ogbuehi KC
Osuagwu UL
Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness
description Kelechi C Ogbuehi, Uchechukwu L OsuagwuOutpatient Clinic, Department of Optometry, King Saud University, Riyadh, Kingdom of Saudi ArabiaBackground: The purpose of this study was to assess the repeatability and limits of agreement of corneal thickness values measured by a high-frequency ultrasound (Artemis-2), hand-held ultrasound pachymeter (DGH-500) and a specular microscope (SP-3000P).Methods: Central corneal thickness (CCT) was analyzed in this prospective randomized study that included 32 patients (18 men and 14 women) aged 21–24 years. Measurements were obtained in two sessions, one week apart, by two examiners with three devices in a randomized order. Nine measurements were taken (three with each device) on one randomly selected eye of each patient in each measurement session. The coefficient of repeatability and interobserver reproducibility for the values of each method were calculated. The limits of agreement between techniques were also evaluated.Results: There were no significant differences in CCT values between sessions for each of the three devices (P > 0.05). The repeatability coefficients for the Artemis-2 (±8 µm/±9 µm) were superior to those of the SP-3000P (±9 µm/±11 µm) and DGH 500 (±12 µm/±12 µm) in session 1/session 2 respectively, while the interobserver reproducibility index (differences between session 1 and session 2) was superior for the SP-3000P (±17 µm) with respect to DHG-500 (±29 µm) and the Artemis-2 (±31 µm). In session 1 and session 2, the limits of agreement between the techniques were 35 µm to -31 µm and 34 to -20 µm, respectively, for DGH-500 versus Artemis-2, 73 µm to 3 µm and 60 µm to 9 µm for Artemis-2 versus SP-3000P, and 58 µm to 22 µm and 72 µm to 10 µm for DGH-500 versus SP-3000P comparisons. The DGH-500 and Artemis-2 gave similar values (P > 0.05) in both sessions, but both (Artemis-2 and DGH-500) values were significantly greater than that of the SP-3000P (P < 0.05) in both sessions.Conclusion: Repeatability was comparably good for the three techniques. However, interobserver reproducibility was approximately twice as good with the SP-3000P compared with the other two devices. The Artemis-2 CCT values consistently agreed with the DGH-500 and less so with the SP-3000P. The Artemis-2 provided CCT values that were, on average, 38 µm and 34 µm greater than that of the SP-3000P in session 1 and session 2, respectively.Keywords: cornea thickness, Artemis-2 ultrasound, hand-held ultrasound, SP-3000P noncontact specular microscopy, reproducibility
format article
author Ogbuehi KC
Osuagwu UL
author_facet Ogbuehi KC
Osuagwu UL
author_sort Ogbuehi KC
title Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness
title_short Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness
title_full Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness
title_fullStr Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness
title_full_unstemmed Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness
title_sort repeatability and interobserver reproducibility of artemis-2 high-frequency ultrasound in determination of human corneal thickness
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/1415c67b314e48ba944d3d7e9bbbe862
work_keys_str_mv AT ogbuehikc repeatabilityandinterobserverreproducibilityofartemis2highfrequencyultrasoundindeterminationofhumancornealthickness
AT osuagwuul repeatabilityandinterobserverreproducibilityofartemis2highfrequencyultrasoundindeterminationofhumancornealthickness
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