SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY

Objective: To screen and identify red cell alloantibodies in multiparous women by red cell panels. Study Design: Cross sectional study. Place and Duration of Study: Army Medical College and Armed Forces Institute of Transfusion in collaboration with Pak Emirates Military Hospital Rawalpindi, d...

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Autores principales:	Sunia Ghaffar, Nasir Uddin, Muhammad Sajid Yazdani, Saleem Ahmed Khan, Samia Ghaffar, Hala Haq
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	blood group systems hemolytic disease of fetus and newborns (hdfn) hemolytic transfusion reactions (htr) Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/141abd3fd13142b5a132a6d7cbe3b2d0
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spelling	oai:doaj.org-article:141abd3fd13142b5a132a6d7cbe3b2d02021-11-11T03:15:23ZSCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY0030-96482411-8842https://doaj.org/article/141abd3fd13142b5a132a6d7cbe3b2d02019-08-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3193/2302https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To screen and identify red cell alloantibodies in multiparous women by red cell panels. Study Design: Cross sectional study. Place and Duration of Study: Army Medical College and Armed Forces Institute of Transfusion in collaboration with Pak Emirates Military Hospital Rawalpindi, duration of study was from 1st Jan 2018 to 31st Aug 2018. Material and Methods: Permission from Institutional Ethical Committee was obtained and blood samples of 200 multiparous women were taken from PEMH Rawalpindi, selected by non-probability consecutive sampling technique. After preliminary workup of ABO and Rh D blood grouping, samples were screened by 3 cell panel to detect presence of red cell alloantibodies and positive results were further identified by 11 cell panel following manufacturer’s instructions. Results: Two Hundreds (200) multiparous women were screened for presence of red cell alloantibodies. The frequency of alloantibodies in multiparous women was 3% (6/200). Most prevalent alloantibody identified was anti-D having frequency of 1.5% (3/6), while other alloantibodies included anti e 0.5% (1/6), Anti K 0.5% (1/6) and insignificant antibody 0.5% (1/6). Conclusion: Our study confirmed that Rh antibodies were most prevalent alloantibodies, out of which anti D was the most frequent alloantibody in Pakistani population while anti e and anti K were present in relatively lower frequency.Sunia GhaffarNasir UddinMuhammad Sajid YazdaniSaleem Ahmed KhanSamia GhaffarHala HaqArmy Medical College Rawalpindiarticleblood group systemshemolytic disease of fetus and newborns (hdfn)hemolytic transfusion reactions (htr)MedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 748-752 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	blood group systems hemolytic disease of fetus and newborns (hdfn) hemolytic transfusion reactions (htr) Medicine R Medicine (General) R5-920
spellingShingle	blood group systems hemolytic disease of fetus and newborns (hdfn) hemolytic transfusion reactions (htr) Medicine R Medicine (General) R5-920 Sunia Ghaffar Nasir Uddin Muhammad Sajid Yazdani Saleem Ahmed Khan Samia Ghaffar Hala Haq SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY
description	Objective: To screen and identify red cell alloantibodies in multiparous women by red cell panels. Study Design: Cross sectional study. Place and Duration of Study: Army Medical College and Armed Forces Institute of Transfusion in collaboration with Pak Emirates Military Hospital Rawalpindi, duration of study was from 1st Jan 2018 to 31st Aug 2018. Material and Methods: Permission from Institutional Ethical Committee was obtained and blood samples of 200 multiparous women were taken from PEMH Rawalpindi, selected by non-probability consecutive sampling technique. After preliminary workup of ABO and Rh D blood grouping, samples were screened by 3 cell panel to detect presence of red cell alloantibodies and positive results were further identified by 11 cell panel following manufacturer’s instructions. Results: Two Hundreds (200) multiparous women were screened for presence of red cell alloantibodies. The frequency of alloantibodies in multiparous women was 3% (6/200). Most prevalent alloantibody identified was anti-D having frequency of 1.5% (3/6), while other alloantibodies included anti e 0.5% (1/6), Anti K 0.5% (1/6) and insignificant antibody 0.5% (1/6). Conclusion: Our study confirmed that Rh antibodies were most prevalent alloantibodies, out of which anti D was the most frequent alloantibody in Pakistani population while anti e and anti K were present in relatively lower frequency.
format	article
author	Sunia Ghaffar Nasir Uddin Muhammad Sajid Yazdani Saleem Ahmed Khan Samia Ghaffar Hala Haq
author_facet	Sunia Ghaffar Nasir Uddin Muhammad Sajid Yazdani Saleem Ahmed Khan Samia Ghaffar Hala Haq
author_sort	Sunia Ghaffar
title	SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY
title_short	SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY
title_full	SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY
title_fullStr	SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY
title_full_unstemmed	SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY
title_sort	screening and identification of red cell alloantibodies in multiparous women, an institution based study
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/141abd3fd13142b5a132a6d7cbe3b2d0
work_keys_str_mv	AT suniaghaffar screeningandidentificationofredcellalloantibodiesinmultiparouswomenaninstitutionbasedstudy AT nasiruddin screeningandidentificationofredcellalloantibodiesinmultiparouswomenaninstitutionbasedstudy AT muhammadsajidyazdani screeningandidentificationofredcellalloantibodiesinmultiparouswomenaninstitutionbasedstudy AT saleemahmedkhan screeningandidentificationofredcellalloantibodiesinmultiparouswomenaninstitutionbasedstudy AT samiaghaffar screeningandidentificationofredcellalloantibodiesinmultiparouswomenaninstitutionbasedstudy AT halahaq screeningandidentificationofredcellalloantibodiesinmultiparouswomenaninstitutionbasedstudy
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SCREENING AND IDENTIFICATION OF RED CELL ALLOANTIBODIES IN MULTIPAROUS WOMEN, AN INSTITUTION BASED STUDY

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