Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis

Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis

Christopher A GirkinUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USAAbstract: Glaucoma disproportionately affects individual of African ancestry. Additionally, racial differences in the optic nerve head have been well described that may alter the vulnerability to intraocul...

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Autor principal: Christopher A Girkin
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2008
Materias:
Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/141c5240d0c84fc097b4805d6fbbe6e1
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spelling oai:doaj.org-article:141c5240d0c84fc097b4805d6fbbe6e12021-12-02T08:28:37ZDifferences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis1177-54671177-5483https://doaj.org/article/141c5240d0c84fc097b4805d6fbbe6e12008-03-01T00:00:00Zhttp://www.dovepress.com/differences-in-optic-nerve-structure-between-individuals-of-predominan-a361https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Christopher A GirkinUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USAAbstract: Glaucoma disproportionately affects individual of African ancestry. Additionally, racial differences in the optic nerve head have been well described that may alter the vulnerability to intraocular pressure related injury and, in addition, alter the clinical ability to detect the presence of early optic nerve injury. This paper will review the literature describing racial differences in the optic nerve head between individuals of African and European ancestry with regards to the potential effects of these differences on the ability to detect glaucoma in different racial groups and to potential differences in the pathogenesis of glaucomatous injury.Keywords: primary open angle glaucoma, African American, optic nerve, optic disc, retinal nerve fiber layer Christopher A GirkinDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 1, Pp 65-69 (2008)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Christopher A Girkin
Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
description Christopher A GirkinUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USAAbstract: Glaucoma disproportionately affects individual of African ancestry. Additionally, racial differences in the optic nerve head have been well described that may alter the vulnerability to intraocular pressure related injury and, in addition, alter the clinical ability to detect the presence of early optic nerve injury. This paper will review the literature describing racial differences in the optic nerve head between individuals of African and European ancestry with regards to the potential effects of these differences on the ability to detect glaucoma in different racial groups and to potential differences in the pathogenesis of glaucomatous injury.Keywords: primary open angle glaucoma, African American, optic nerve, optic disc, retinal nerve fiber layer
format article
author Christopher A Girkin
author_facet Christopher A Girkin
author_sort Christopher A Girkin
title Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_short Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_full Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_fullStr Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_full_unstemmed Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_sort differences in optic nerve structure between individuals of predominantly african and european ancestry: implications for disease detection and pathogenesis
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/141c5240d0c84fc097b4805d6fbbe6e1
work_keys_str_mv AT christopheragirkin differencesinopticnervestructurebetweenindividualsofpredominantlyafricanandeuropeanancestryimplicationsfordiseasedetectionandpathogenesis
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