Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury

HGF is one of the factors taking part in regeneration and recovery of liver after injury. The article is dedicated to the study of influence of single HGF intake on the indices of non-specific immune response in rats after 70% liver resection in the early postoperative period. Research was conducted...

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Autores principales:	S. A. Lepekhova, L. V. Zaritskaya, E. V. Batunova, K. A. Apartsin, O. N. Postovaya, I. S. Kurganskiy, M. V. Prokopjev, E. V. Koval, P. S. Makoshina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	hepatic failure hepatocyte growth factor non-specific resistance inflammation Science Q
Acceso en línea:	https://doaj.org/article/141d7f39b3154003a83e0dd05af7826e
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spelling	oai:doaj.org-article:141d7f39b3154003a83e0dd05af7826e2021-11-23T06:14:33ZEffect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury2541-94202587-959610.12737/21485https://doaj.org/article/141d7f39b3154003a83e0dd05af7826e2016-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/154https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596HGF is one of the factors taking part in regeneration and recovery of liver after injury. The article is dedicated to the study of influence of single HGF intake on the indices of non-specific immune response in rats after 70% liver resection in the early postoperative period. Research was conducted on 42 six-months white male Wistar rats of 250-300 g. It was revealed that level of segmentonuclear neutrophils and lymphocytes in the group with HGF intake stand at normal level on the 2nd day and normalizes to the 11th day that testifies to the decrease of inflammatory response. Increased level of leukocytes and monocytes is registered in the group with HGF intake. Also integrity of non-specific resistance in the early postoperative period on the 2nd day is registered. Suppression of phagocytosis indices with preservation of functional activity of phagocytes was registered to the 11th day.S. A. LepekhovaL. V. ZaritskayaE. V. BatunovaK. A. ApartsinO. N. PostovayaI. S. KurganskiyM. V. ProkopjevE. V. KovalP. S. MakoshinaScientific Сentre for Family Health and Human Reproduction Problemsarticlehepatic failurehepatocyte growth factornon-specific resistanceinflammationScienceQRUActa Biomedica Scientifica, Vol 1, Iss 1, Pp 49-55 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	hepatic failure hepatocyte growth factor non-specific resistance inflammation Science Q
spellingShingle	hepatic failure hepatocyte growth factor non-specific resistance inflammation Science Q S. A. Lepekhova L. V. Zaritskaya E. V. Batunova K. A. Apartsin O. N. Postovaya I. S. Kurganskiy M. V. Prokopjev E. V. Koval P. S. Makoshina Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury
description	HGF is one of the factors taking part in regeneration and recovery of liver after injury. The article is dedicated to the study of influence of single HGF intake on the indices of non-specific immune response in rats after 70% liver resection in the early postoperative period. Research was conducted on 42 six-months white male Wistar rats of 250-300 g. It was revealed that level of segmentonuclear neutrophils and lymphocytes in the group with HGF intake stand at normal level on the 2nd day and normalizes to the 11th day that testifies to the decrease of inflammatory response. Increased level of leukocytes and monocytes is registered in the group with HGF intake. Also integrity of non-specific resistance in the early postoperative period on the 2nd day is registered. Suppression of phagocytosis indices with preservation of functional activity of phagocytes was registered to the 11th day.
format	article
author	S. A. Lepekhova L. V. Zaritskaya E. V. Batunova K. A. Apartsin O. N. Postovaya I. S. Kurganskiy M. V. Prokopjev E. V. Koval P. S. Makoshina
author_facet	S. A. Lepekhova L. V. Zaritskaya E. V. Batunova K. A. Apartsin O. N. Postovaya I. S. Kurganskiy M. V. Prokopjev E. V. Koval P. S. Makoshina
author_sort	S. A. Lepekhova
title	Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury
title_short	Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury
title_full	Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury
title_fullStr	Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury
title_full_unstemmed	Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury
title_sort	effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/141d7f39b3154003a83e0dd05af7826e
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Effect of single intake of exogenous hepatocytes growth inducer on the indices of non-specific resistance under conditions of postresection liver injury

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