Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis

Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by skin and joint involvement. The disease may present with various joint pattern involvement, which sometimes may lead to joint destruction and deformity. Early diagnosis and treatment with disease-modifying anti-rheumatic dr...

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Autores principales:	Fusun Gediz, Mehmet Can Ugur, Meltem Turkmen, Senol Kobak
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2021
Materias:	psoriatic arthritis ustekinumab chronic lymphocytic leukemia. Medicine R
Acceso en línea:	https://doaj.org/article/141f651f5b3f4b3ab69770712b9362bb
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spelling	oai:doaj.org-article:141f651f5b3f4b3ab69770712b9362bb2021-12-02T18:55:18ZUstekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis0034-62332084-983410.5114/reum.2021.102618https://doaj.org/article/141f651f5b3f4b3ab69770712b9362bb2021-02-01T00:00:00Zhttps://www.termedia.pl/Ustekinumab-induced-chronic-lymphocytic-leukemia-in-a-patient-with-psoriatic-arthritis,18,42983,1,1.htmlhttps://doaj.org/toc/0034-6233https://doaj.org/toc/2084-9834Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by skin and joint involvement. The disease may present with various joint pattern involvement, which sometimes may lead to joint destruction and deformity. Early diagnosis and treatment with disease-modifying anti-rheumatic drugs may prevent joint deformity. Recently there are many new treatment options including biologic drugs. Ustekinumab, an interleukin 12/23 inhibitor, has proven efficacy in the treatment of psoriatic arthritis. Like other biologic drugs (anti-TNF-), there are contradictory data about the safety of ustekinumab and possible relationship with cancer development. Herein we report the development of chronic lymphocytic leukemia in a patient with PsA treated with ustekinumab.Fusun GedizMehmet Can UgurMeltem TurkmenSenol KobakTermedia Publishing Housearticlepsoriatic arthritis ustekinumab chronic lymphocytic leukemia.MedicineRENRheumatology, Vol 59, Iss 1, Pp 58-61 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	psoriatic arthritis ustekinumab chronic lymphocytic leukemia. Medicine R
spellingShingle	psoriatic arthritis ustekinumab chronic lymphocytic leukemia. Medicine R Fusun Gediz Mehmet Can Ugur Meltem Turkmen Senol Kobak Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis
description	Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by skin and joint involvement. The disease may present with various joint pattern involvement, which sometimes may lead to joint destruction and deformity. Early diagnosis and treatment with disease-modifying anti-rheumatic drugs may prevent joint deformity. Recently there are many new treatment options including biologic drugs. Ustekinumab, an interleukin 12/23 inhibitor, has proven efficacy in the treatment of psoriatic arthritis. Like other biologic drugs (anti-TNF-), there are contradictory data about the safety of ustekinumab and possible relationship with cancer development. Herein we report the development of chronic lymphocytic leukemia in a patient with PsA treated with ustekinumab.
format	article
author	Fusun Gediz Mehmet Can Ugur Meltem Turkmen Senol Kobak
author_facet	Fusun Gediz Mehmet Can Ugur Meltem Turkmen Senol Kobak
author_sort	Fusun Gediz
title	Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis
title_short	Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis
title_full	Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis
title_fullStr	Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis
title_full_unstemmed	Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis
title_sort	ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis
publisher	Termedia Publishing House
publishDate	2021
url	https://doaj.org/article/141f651f5b3f4b3ab69770712b9362bb
work_keys_str_mv	AT fusungediz ustekinumabinducedchroniclymphocyticleukemiainapatientwithpsoriaticarthritis AT mehmetcanugur ustekinumabinducedchroniclymphocyticleukemiainapatientwithpsoriaticarthritis AT meltemturkmen ustekinumabinducedchroniclymphocyticleukemiainapatientwithpsoriaticarthritis AT senolkobak ustekinumabinducedchroniclymphocyticleukemiainapatientwithpsoriaticarthritis
_version_	1718377249773715456

Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis

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