Th2 and eosinophil responses suppress inflammatory arthritis
Type 2 immune responses are viewed as opposites of Type 1 and 17 responses. Here the authors show that activation of Type 2 immunity by helminth infection counteracts the development of inflammatory arthritis, a type 17-mediated pathology, via IL-4/IL-13- STAT6 signalling and eosinophil activation.
Guardado en:
Autores principales: | Zhu Chen, Darja Andreev, Katharina Oeser, Branislav Krljanac, Axel Hueber, Arnd Kleyer, David Voehringer, Georg Schett, Aline Bozec |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/14215b3bc91c4884a29bc4560ad6b232 |
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