Combined burden and functional impact tests for cancer driver discovery using DriverPower

Combined burden and functional impact tests for cancer driver discovery using DriverPower

Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer who...

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Autores principales: Shimin Shuai, PCAWG Drivers and Functional Interpretation Working Group, Steven Gallinger, Lincoln Stein, PCAWG Consortium
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/142b65513ccf441182a79c2cf78b29df
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