The roles and mechanisms of the m6A reader protein YTHDF1 in tumor biology and human diseases

YTHDF1 is the most versatile and powerful reader protein of N6-methyladenosine (m6A)-modified RNA, and it can recognize both G(m6A)C and A(m6A)C RNAs as ligands without sequence selectivity. YTHDF1 regulates target gene expression by different mechanisms, such as promoting translation or regulating...

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Detalles Bibliográficos
Autores principales: Zuyao Chen, Xiaolin Zhong, Min Xia, Jing Zhong
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
m6A
Acceso en línea:https://doaj.org/article/142ccd92499b4b4d8c3601d6ecd4dc60
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