Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments.

Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments.

<h4>Background</h4>PDZ domains are highly abundant protein-protein interaction modules involved in the wiring of protein networks. Emerging evidence indicates that some PDZ domains also interact with phosphoinositides (PtdInsPs), important regulators of cell polarization and signaling. Y...

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Autores principales: Ylva Ivarsson, Anna Maria Wawrzyniak, Rudra Kashyap, Jolanta Polanowska, Stéphane Betzi, Frédérique Lembo, Elke Vermeiren, Driss Chiheb, Nicolas Lenfant, Xavier Morelli, Jean-Paul Borg, Jérôme Reboul, Pascale Zimmermann
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/143072234673423495c99d71c32bc8cf
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