Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis

Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis

Summary: Fibrosis-driven solid organ failure is an enormous burden on global health. Spiny mice (Acomys) are terrestrial mammals that can regenerate severe skin wounds without scars to avoid predation. Whether spiny mice also regenerate internal organ injuries is unknown. Here, we show that despite...

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Autores principales: Daryl M. Okamura, Chris M. Brewer, Paul Wakenight, Nadia Bahrami, Kristina Bernardi, Amy Tran, Jill Olson, Xiaogang Shi, Szu-Ying Yeh, Adrian Piliponsky, Sarah J. Collins, Elizabeth D. Nguyen, Andrew E. Timms, James W. MacDonald, Theo K. Bammler, Branden R. Nelson, Kathleen J. Millen, David R. Beier, Mark W. Majesky
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Animal physiology
Molecular biology
Developmental biology
Science
Q
Acceso en línea:https://doaj.org/article/14339f301a224e7fbcad8ed0416f3953
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