A Thermodynamic Model for Interpreting Tryptophan Excitation-Energy-Dependent Fluorescence Spectra Provides Insight Into Protein Conformational Sampling and Stability

It is now over 30 years since Demchenko and Ladokhin first posited the potential of the tryptophan red edge excitation shift (REES) effect to capture information on protein molecular dynamics. While there have been many key efforts in the intervening years, a biophysical thermodynamic model to quant...

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Auteurs principaux: A Kwok, IS Camacho, S Winter, M Knight, RM Meade, MW Van der Kamp, A Turner, J O’Hara, JM Mason, AR Jones, VL Arcus, CR Pudney
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/1439860014ea47359cd6861b3f8b4edf
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