A Thermodynamic Model for Interpreting Tryptophan Excitation-Energy-Dependent Fluorescence Spectra Provides Insight Into Protein Conformational Sampling and Stability

It is now over 30 years since Demchenko and Ladokhin first posited the potential of the tryptophan red edge excitation shift (REES) effect to capture information on protein molecular dynamics. While there have been many key efforts in the intervening years, a biophysical thermodynamic model to quant...

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Autores principales: A Kwok, IS Camacho, S Winter, M Knight, RM Meade, MW Van der Kamp, A Turner, J O’Hara, JM Mason, AR Jones, VL Arcus, CR Pudney
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/1439860014ea47359cd6861b3f8b4edf
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