Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties
Adeno-associated viruses (AAVs) are vehicles for gene therapy in humans, but currently only a limited amount of AAV serotypes is available. Here, the authors identify a novel AAV, AAVv66, and demonstrate enhanced production yields, virion stability, and CNS transduction compared to the clinically ap...
Guardado en:
Autores principales: | Hung-Lun Hsu, Alexander Brown, Anna B. Loveland, Anoushka Lotun, Meiyu Xu, Li Luo, Guangchao Xu, Jia Li, Lingzhi Ren, Qin Su, Dominic J. Gessler, Yuquan Wei, Phillip W. L. Tai, Andrei A. Korostelev, Guangping Gao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/143cfb7a1596401ea3955f040a832c0f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Adeno-associated virus capsid assembly is divergent and stochastic
por: Tobias P. Wörner, et al.
Publicado: (2021) -
Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
por: Yeonsoo Yoon, et al.
Publicado: (2018) -
Divergent engagements between adeno-associated viruses with their cellular receptor AAVR
por: Ran Zhang, et al.
Publicado: (2019) -
Neurotropic effects of respiratory viral infections: mental and neuropsychological aspects
por: A.A. Shuprovich
Publicado: (2021) -
Genomic diversity contributes to the neuroinvasiveness of the Yellow fever French neurotropic vaccine
por: Florian Bakoa, et al.
Publicado: (2021)