Programmed loading and rapid purification of engineered bacterial microcompartment shells

Bacterial microcompartments are protein-bound organelles encapsulating segments of metabolic pathways. Here the authors functionalise shell proteins to facilitate facile purification and enable cargo encapsulation via covalent linkage.

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Detalles Bibliográficos
Autores principales: Andrew Hagen, Markus Sutter, Nancy Sloan, Cheryl A. Kerfeld
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
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Acceso en línea:https://doaj.org/article/143e49afb4e3490587e969b41fc5612e
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Descripción
Sumario:Bacterial microcompartments are protein-bound organelles encapsulating segments of metabolic pathways. Here the authors functionalise shell proteins to facilitate facile purification and enable cargo encapsulation via covalent linkage.