A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A
A signal-enhanced lateral flow strip biosensor has been constructed for ultrasensitive and on-site visual detection of bisphenol A (BPA). The signal amplification principle is based on the capacity of binding a large number of antibody-assembled gold nanoparticle (AuNP–antibody) conjugates of the po...
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Taylor & Francis Group
2018
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oai:doaj.org-article:143ef199d7ec465a9fb771435aca75c42021-11-26T11:19:46ZA signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A0954-01051465-344310.1080/09540105.2017.1365822https://doaj.org/article/143ef199d7ec465a9fb771435aca75c42018-01-01T00:00:00Zhttp://dx.doi.org/10.1080/09540105.2017.1365822https://doaj.org/toc/0954-0105https://doaj.org/toc/1465-3443A signal-enhanced lateral flow strip biosensor has been constructed for ultrasensitive and on-site visual detection of bisphenol A (BPA). The signal amplification principle is based on the capacity of binding a large number of antibody-assembled gold nanoparticle (AuNP–antibody) conjugates of the poly amidoamine (PAMAM), which bears a multitude of amino groups. This signal-enhanced method could achieve BPA detection at 10 ppb based on naked eye visual observation, which represents an at least 50-fold improvement of the sensitivity of a traditional method without PAMAM. Moreover, good linearity was observed in the range from 2 to 100 ppb after quantitative analysis using the ImageJ software. This signal amplification method could be adopted as a potential generous technique in different fields.Xiayu PengLichao KangFangqin PangHongmin LiRuifeng LuoXiaoling LuoFengxia SunTaylor & Francis Grouparticlelateral flow stripsignal amplificationbpafood safetyAgriculture (General)S1-972Immunologic diseases. AllergyRC581-607ENFood and Agricultural Immunology, Vol 29, Iss 1, Pp 216-227 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
lateral flow strip signal amplification bpa food safety Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 |
| spellingShingle |
lateral flow strip signal amplification bpa food safety Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 Xiayu Peng Lichao Kang Fangqin Pang Hongmin Li Ruifeng Luo Xiaoling Luo Fengxia Sun A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A |
| description |
A signal-enhanced lateral flow strip biosensor has been constructed for ultrasensitive and on-site visual detection of bisphenol A (BPA). The signal amplification principle is based on the capacity of binding a large number of antibody-assembled gold nanoparticle (AuNP–antibody) conjugates of the poly amidoamine (PAMAM), which bears a multitude of amino groups. This signal-enhanced method could achieve BPA detection at 10 ppb based on naked eye visual observation, which represents an at least 50-fold improvement of the sensitivity of a traditional method without PAMAM. Moreover, good linearity was observed in the range from 2 to 100 ppb after quantitative analysis using the ImageJ software. This signal amplification method could be adopted as a potential generous technique in different fields. |
| format |
article |
| author |
Xiayu Peng Lichao Kang Fangqin Pang Hongmin Li Ruifeng Luo Xiaoling Luo Fengxia Sun |
| author_facet |
Xiayu Peng Lichao Kang Fangqin Pang Hongmin Li Ruifeng Luo Xiaoling Luo Fengxia Sun |
| author_sort |
Xiayu Peng |
| title |
A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A |
| title_short |
A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A |
| title_full |
A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A |
| title_fullStr |
A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A |
| title_full_unstemmed |
A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A |
| title_sort |
signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol a |
| publisher |
Taylor & Francis Group |
| publishDate |
2018 |
| url |
https://doaj.org/article/143ef199d7ec465a9fb771435aca75c4 |
| work_keys_str_mv |
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| _version_ |
1718409520564142080 |