KCNQ channels regulate age-related memory impairment.
In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of epilepsy. The M-current has been shown to be a key regulator of neuronal plasticity underlying associative memory and ethanol response in mammals. Previous work ha...
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Autores principales: | Sonia Cavaliere, Bilal R Malik, James J L Hodge |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/1442a60120534175981982cfe0f069ed |
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