Designed Ankyrin Repeat Protein (DARPin) Neutralizers of TcdB from <named-content content-type="genus-species">Clostridium difficile</named-content> Ribotype 027

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Designed Ankyrin Repeat Protein (DARPin) Neutralizers of TcdB from <named-content content-type="genus-species">Clostridium difficile</named-content> Ribotype 027

ABSTRACT Clostridium difficile infection (CDI) is a leading cause of hospital-acquired diarrhea. In recent decades, the emergence of the “hypervirulent” BI/NAP1/027 strains of C. difficile significantly increased the morbidity and mortality of CDI. The pathogenesis of CDI is primarily mediated by th...

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Autores principales:	Zeyu Peng, Rudo Simeon, Samuel B. Mitchell, Junjie Zhang, Hanping Feng, Zhilei Chen
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	toxin therapeutic infection protein antibody hypervirulent Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/144a26aa4c874833b3124d220b7faf2a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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