Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan<sup>®</sup> (Semisolid) Formulation Using Human Skin and a Transdermal Diffusion Test Model
The effect of transdermal vehicle (Pentravan<sup>®</sup>) on skin permeability was examined for unmodified ibuprofen (IBU) and ion pairs of ibuprofen with new L-valine alkyl esters [ValOR][IBU]. The percutaneous permeation across the human skin and transdermal diffusion test model (Strat...
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Main Authors: | Paula Ossowicz-Rupniewska, Anna Nowak, Joanna Klebeko, Ewa Janus, Wiktoria Duchnik, Urszula Adamiak-Giera, Łukasz Kucharski, Piotr Prowans, Jan Petriczko, Norbert Czapla, Piotr Bargiel, Marta Markowska, Adam Klimowicz |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/144d7e5965b542cfa010b0e7e661aa1b |
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