Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan<sup>®</sup> (Semisolid) Formulation Using Human Skin and a Transdermal Diffusion Test Model

The effect of transdermal vehicle (Pentravan<sup>®</sup>) on skin permeability was examined for unmodified ibuprofen (IBU) and ion pairs of ibuprofen with new L-valine alkyl esters [ValOR][IBU]. The percutaneous permeation across the human skin and transdermal diffusion test model (Strat...

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Auteurs principaux:	Paula Ossowicz-Rupniewska, Anna Nowak, Joanna Klebeko, Ewa Janus, Wiktoria Duchnik, Urszula Adamiak-Giera, Łukasz Kucharski, Piotr Prowans, Jan Petriczko, Norbert Czapla, Piotr Bargiel, Marta Markowska, Adam Klimowicz
Format:	article
Langue:	EN
Publié:	MDPI AG 2021
Sujets:	structural modification of ibuprofen increasing drug permeability Franz cell diffusion transdermal delivery system Pentravan<sup>®</sup> human skin Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85
Accès en ligne:	https://doaj.org/article/144d7e5965b542cfa010b0e7e661aa1b
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Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan<sup>®</sup> (Semisolid) Formulation Using Human Skin and a Transdermal Diffusion Test Model

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