Structure-Activity Relationships of Holothuroid’s Triterpene Glycosides and Some In Silico Insights Obtained by Molecular Dynamics Study on the Mechanisms of Their Membranolytic Action

The article describes the structure-activity relationships (SAR) for a broad series of sea cucumber glycosides on different tumor cell lines and erythrocytes, and an in silico modulation of the interaction of selected glycosides from the sea cucumber <em>Eupentacta fraudatrix</em> with m...

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Bibliographic Details
Main Authors: Elena A. Zelepuga, Alexandra S. Silchenko, Sergey A. Avilov, Vladimir I. Kalinin
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
Online Access:https://doaj.org/article/1450beb8dfc34cc1b6dae325f016ed29
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