Sulfonate-modified phenylboronic acid-rich nanoparticles as a novel mucoadhesive drug delivery system for vaginal administration of protein therapeutics: improved stability, mucin-dependent release and effective intravaginal placement

Sulfonate-modified phenylboronic acid-rich nanoparticles as a novel mucoadhesive drug delivery system for vaginal administration of protein therapeutics: improved stability, mucin-dependent release and effective intravaginal placement

ChunYan Li,1 ZhiGang Huang,2 ZheShuo Liu,1 LiQian Ci,3 ZhePeng Liu,3 Yu Liu,2 XueYing Yan,1 WeiYue Lu2 1School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, 2Department of Pharmaceutics, School of Pharmacy, Key Laboratory of Smart Drug Delivery, Ministry of Edu...

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Autores principales: Li CY, Huang ZG, Liu ZS, Ci LQ, Liu ZP, Liu Y, Yan XY, Lu WY
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
Materias:
Mucoadhesion
phenylboronic acid
stability
controlled-release
protein therapeutics
nanoparticles
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/146123e0df6545a59a78a646daf24f2f
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