Three <italic toggle="yes">Toxoplasma gondii</italic> Dense Granule Proteins Are Required for Induction of Lewis Rat Macrophage Pyroptosis

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Three <italic toggle="yes">Toxoplasma gondii</italic> Dense Granule Proteins Are Required for Induction of Lewis Rat Macrophage Pyroptosis

ABSTRACT Upon invasion of Lewis rat macrophages, Toxoplasma rapidly induces programmed cell death (pyroptosis), which prevents Toxoplasma replication, possibly explaining the resistance of the Lewis rat to Toxoplasma. Using a chemical mutagenesis screen, we identified Toxoplasma mutants that no long...

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Autores principales:	Yifan Wang, Kimberly M. Cirelli, Patricio D. C. Barros, Lamba Omar Sangaré, Vincent Butty, Musa A. Hassan, Patricia Pesavento, Asli Mete, Jeroen P. J. Saeij
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	Dense granule proteins macrophages NLRP1 inflammasomes pyroptosis Toxoplasma gondii Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/1462382b1c284276b4916c2eb582db60
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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