MitomiRs: their roles in mitochondria and importance in cancer cell metabolism

MicroRNAs (miRNAs) are short non-coding RNAs that play important roles in almost all biological pathways. They regulate post-transcriptional gene expression by binding to the 3’untranslated region (3’UTR) of messenger RNAs (mRNAs). MitomiRs are miRNAs of nuclear or mitochondrial origin that are loca...

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Autores principales: Rencelj Andrej, Gvozdenovic Nada, Cemazar Maja
Formato: article
Lenguaje:EN
Publicado: Sciendo 2021
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Acceso en línea:https://doaj.org/article/1469eb1f0451409ca66c7e70ead926e4
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spelling oai:doaj.org-article:1469eb1f0451409ca66c7e70ead926e42021-12-05T14:11:10ZMitomiRs: their roles in mitochondria and importance in cancer cell metabolism1581-320710.2478/raon-2021-0042https://doaj.org/article/1469eb1f0451409ca66c7e70ead926e42021-11-01T00:00:00Zhttps://doi.org/10.2478/raon-2021-0042https://doaj.org/toc/1581-3207MicroRNAs (miRNAs) are short non-coding RNAs that play important roles in almost all biological pathways. They regulate post-transcriptional gene expression by binding to the 3’untranslated region (3’UTR) of messenger RNAs (mRNAs). MitomiRs are miRNAs of nuclear or mitochondrial origin that are localized in mitochondria and have a crucial role in regulation of mitochondrial function and metabolism. In eukaryotes, mitochondria are the major sites of oxidative metabolism of sugars, lipids, amino acids, and other bio-macromolecules. They are also the main sites of adenosine triphosphate (ATP) production.Rencelj AndrejGvozdenovic NadaCemazar MajaSciendoarticlemicrornasmitomirmitochondriacancercancer cell metabolismMedical physics. Medical radiology. Nuclear medicineR895-920ENRadiology and Oncology, Vol 55, Iss 4, Pp 379-392 (2021)
institution DOAJ
collection DOAJ
language EN
topic micrornas
mitomir
mitochondria
cancer
cancer cell metabolism
Medical physics. Medical radiology. Nuclear medicine
R895-920
spellingShingle micrornas
mitomir
mitochondria
cancer
cancer cell metabolism
Medical physics. Medical radiology. Nuclear medicine
R895-920
Rencelj Andrej
Gvozdenovic Nada
Cemazar Maja
MitomiRs: their roles in mitochondria and importance in cancer cell metabolism
description MicroRNAs (miRNAs) are short non-coding RNAs that play important roles in almost all biological pathways. They regulate post-transcriptional gene expression by binding to the 3’untranslated region (3’UTR) of messenger RNAs (mRNAs). MitomiRs are miRNAs of nuclear or mitochondrial origin that are localized in mitochondria and have a crucial role in regulation of mitochondrial function and metabolism. In eukaryotes, mitochondria are the major sites of oxidative metabolism of sugars, lipids, amino acids, and other bio-macromolecules. They are also the main sites of adenosine triphosphate (ATP) production.
format article
author Rencelj Andrej
Gvozdenovic Nada
Cemazar Maja
author_facet Rencelj Andrej
Gvozdenovic Nada
Cemazar Maja
author_sort Rencelj Andrej
title MitomiRs: their roles in mitochondria and importance in cancer cell metabolism
title_short MitomiRs: their roles in mitochondria and importance in cancer cell metabolism
title_full MitomiRs: their roles in mitochondria and importance in cancer cell metabolism
title_fullStr MitomiRs: their roles in mitochondria and importance in cancer cell metabolism
title_full_unstemmed MitomiRs: their roles in mitochondria and importance in cancer cell metabolism
title_sort mitomirs: their roles in mitochondria and importance in cancer cell metabolism
publisher Sciendo
publishDate 2021
url https://doaj.org/article/1469eb1f0451409ca66c7e70ead926e4
work_keys_str_mv AT renceljandrej mitomirstheirrolesinmitochondriaandimportanceincancercellmetabolism
AT gvozdenovicnada mitomirstheirrolesinmitochondriaandimportanceincancercellmetabolism
AT cemazarmaja mitomirstheirrolesinmitochondriaandimportanceincancercellmetabolism
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