Artificially decreasing cortical tension generates aneuploidy in mouse oocytes
The developmental potential of human and murine oocytes is predicted by their mechanical properties. Here the authors show that artificial reduction of cortex tension produces aneuploid mouse oocytes and speculate that this may contribute to the high aneuploidy rate typical of female meiosis.
Guardado en:
Autores principales: | Isma Bennabi, Flora Crozet, Elvira Nikalayevich, Agathe Chaigne, Gaëlle Letort, Marion Manil-Ségalen, Clément Campillo, Clotilde Cadart, Alice Othmani, Rafaele Attia, Auguste Genovesio, Marie-Hélène Verlhac, Marie-Emilie Terret |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/147621511e274dd9a875526215004355 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
F-actin mechanics control spindle centring in the mouse zygote
por: Agathe Chaigne, et al.
Publicado: (2016) -
Molecular signatures of aneuploidy-driven adaptive evolution
por: Alaattin Kaya, et al.
Publicado: (2020) -
Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
por: Clotilde Cadart, et al.
Publicado: (2018) -
Chromosome arm aneuploidies shape tumour evolution and drug response
por: Ankit Shukla, et al.
Publicado: (2020) -
Single cell transcriptome in aneuploidies reveals mechanisms of gene dosage imbalance
por: Georgios Stamoulis, et al.
Publicado: (2019)