Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control
Lamiophlomis rotata (Benth.) Kudo (LR) is an extensively used Chinese herbal medicine. It contains a variety of chemical constituents with significant biological activities that were first recorded in the classical masterpiece of Tibetan Medicine, Somaratsa. In this review, we summarize the informat...
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2021
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oai:doaj.org-article:148068fb3cbb45d39959233cfc16a5fb2021-11-14T04:29:22ZLamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control0753-332210.1016/j.biopha.2021.112299https://doaj.org/article/148068fb3cbb45d39959233cfc16a5fb2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0753332221010830https://doaj.org/toc/0753-3322Lamiophlomis rotata (Benth.) Kudo (LR) is an extensively used Chinese herbal medicine. It contains a variety of chemical constituents with significant biological activities that were first recorded in the classical masterpiece of Tibetan Medicine, Somaratsa. In this review, we summarize the information regarding the traditional uses, chemical constituents, pharmacological effects, clinical applications, quality control, toxicology, and pharmacokinetics of LR. At least 223 chemical constituents have been isolated from LR, including phenylethanoid glycosides, flavonoids, iridoids, volatile oils, et al. Their various physiological activities have been demonstrated as analgesic, hemostatic, anti-inflammatory, anti-tumor, marrow-supplementing, anti-bacterial, and immunity-strengthening. The clinical applications of LR and quality control are also discussed, as well as some existing problems. This article aims to provide more comprehensive information on the chemical composition, pharmacological activity, and clinical application of LR, so as to provide a theoretical basis for the further reasonable development of LR in clinical practice and of new drugs.Yu LiFang LiTing-ting ZhengLei ShiZhi-gang ZhangTian-mei NiuQiu-yue WangDong-sheng ZhaoWei LiPan ZhaoElsevierarticleLamiophlomis rotata (Benth.) Kudo (LR)Traditional usesChemical constituentsPharmacologyQuality controlClinical applicationsTherapeutics. PharmacologyRM1-950ENBiomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112299- (2021) |
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DOAJ |
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Lamiophlomis rotata (Benth.) Kudo (LR) Traditional uses Chemical constituents Pharmacology Quality control Clinical applications Therapeutics. Pharmacology RM1-950 |
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Lamiophlomis rotata (Benth.) Kudo (LR) Traditional uses Chemical constituents Pharmacology Quality control Clinical applications Therapeutics. Pharmacology RM1-950 Yu Li Fang Li Ting-ting Zheng Lei Shi Zhi-gang Zhang Tian-mei Niu Qiu-yue Wang Dong-sheng Zhao Wei Li Pan Zhao Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control |
| description |
Lamiophlomis rotata (Benth.) Kudo (LR) is an extensively used Chinese herbal medicine. It contains a variety of chemical constituents with significant biological activities that were first recorded in the classical masterpiece of Tibetan Medicine, Somaratsa. In this review, we summarize the information regarding the traditional uses, chemical constituents, pharmacological effects, clinical applications, quality control, toxicology, and pharmacokinetics of LR. At least 223 chemical constituents have been isolated from LR, including phenylethanoid glycosides, flavonoids, iridoids, volatile oils, et al. Their various physiological activities have been demonstrated as analgesic, hemostatic, anti-inflammatory, anti-tumor, marrow-supplementing, anti-bacterial, and immunity-strengthening. The clinical applications of LR and quality control are also discussed, as well as some existing problems. This article aims to provide more comprehensive information on the chemical composition, pharmacological activity, and clinical application of LR, so as to provide a theoretical basis for the further reasonable development of LR in clinical practice and of new drugs. |
| format |
article |
| author |
Yu Li Fang Li Ting-ting Zheng Lei Shi Zhi-gang Zhang Tian-mei Niu Qiu-yue Wang Dong-sheng Zhao Wei Li Pan Zhao |
| author_facet |
Yu Li Fang Li Ting-ting Zheng Lei Shi Zhi-gang Zhang Tian-mei Niu Qiu-yue Wang Dong-sheng Zhao Wei Li Pan Zhao |
| author_sort |
Yu Li |
| title |
Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control |
| title_short |
Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control |
| title_full |
Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control |
| title_fullStr |
Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control |
| title_full_unstemmed |
Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control |
| title_sort |
lamiophlomis herba: a comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control |
| publisher |
Elsevier |
| publishDate |
2021 |
| url |
https://doaj.org/article/148068fb3cbb45d39959233cfc16a5fb |
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