A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging

Detection of the tumour boundary in prostate cancer is required for surgery. Here the authors present a fluorescent molecular rotor probe to target a prostate cancer marker, prostate-specific membrane antigen (PSMA), which they use in a xenograft mouse model to show it can be used for in vivo imagin...

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Autores principales: Jingming Zhang, Anastasia Rakhimbekova, Xiaojiang Duan, Qingqing Yin, Catherine A. Foss, Yan Fan, Yangyang Xu, Xuesong Li, Xuekang Cai, Zsofia Kutil, Pengyuan Wang, Zhi Yang, Ning Zhang, Martin G. Pomper, Yiguang Wang, Cyril Bařinka, Xing Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1499e26d72784107a349a5e409a372d7
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spelling oai:doaj.org-article:1499e26d72784107a349a5e409a372d72021-12-02T15:31:37ZA prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging10.1038/s41467-021-25746-62041-1723https://doaj.org/article/1499e26d72784107a349a5e409a372d72021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25746-6https://doaj.org/toc/2041-1723Detection of the tumour boundary in prostate cancer is required for surgery. Here the authors present a fluorescent molecular rotor probe to target a prostate cancer marker, prostate-specific membrane antigen (PSMA), which they use in a xenograft mouse model to show it can be used for in vivo imaging.Jingming ZhangAnastasia RakhimbekovaXiaojiang DuanQingqing YinCatherine A. FossYan FanYangyang XuXuesong LiXuekang CaiZsofia KutilPengyuan WangZhi YangNing ZhangMartin G. PomperYiguang WangCyril BařinkaXing YangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jingming Zhang
Anastasia Rakhimbekova
Xiaojiang Duan
Qingqing Yin
Catherine A. Foss
Yan Fan
Yangyang Xu
Xuesong Li
Xuekang Cai
Zsofia Kutil
Pengyuan Wang
Zhi Yang
Ning Zhang
Martin G. Pomper
Yiguang Wang
Cyril Bařinka
Xing Yang
A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
description Detection of the tumour boundary in prostate cancer is required for surgery. Here the authors present a fluorescent molecular rotor probe to target a prostate cancer marker, prostate-specific membrane antigen (PSMA), which they use in a xenograft mouse model to show it can be used for in vivo imaging.
format article
author Jingming Zhang
Anastasia Rakhimbekova
Xiaojiang Duan
Qingqing Yin
Catherine A. Foss
Yan Fan
Yangyang Xu
Xuesong Li
Xuekang Cai
Zsofia Kutil
Pengyuan Wang
Zhi Yang
Ning Zhang
Martin G. Pomper
Yiguang Wang
Cyril Bařinka
Xing Yang
author_facet Jingming Zhang
Anastasia Rakhimbekova
Xiaojiang Duan
Qingqing Yin
Catherine A. Foss
Yan Fan
Yangyang Xu
Xuesong Li
Xuekang Cai
Zsofia Kutil
Pengyuan Wang
Zhi Yang
Ning Zhang
Martin G. Pomper
Yiguang Wang
Cyril Bařinka
Xing Yang
author_sort Jingming Zhang
title A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
title_short A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
title_full A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
title_fullStr A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
title_full_unstemmed A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
title_sort prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1499e26d72784107a349a5e409a372d7
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