5-<i>epi</i>-Sinuleptolide from Soft Corals of the Genus <i>Sinularia</i> Exerts Cytotoxic Effects on Pancreatic Cancer Cell Lines via the Inhibition of JAK2/STAT3, AKT, and ERK Activity
Pancreatic ductal adenocarcinoma is one of the most lethal malignancies: more than half of patients are diagnosed with a metastatic disease, which is associated with a five-year survival rate of only 3%. 5-<i>epi</i>-Sinuleptolide, a norditerpene isolated from <i>Sinularia</i>...
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Autores principales: | Wan-Chi Tsai, Wen-Hung Wang, Bo-Cian Huang, Chiung-Yao Huang, Jyh-Horng Sheu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/149d14d5b9cc4beba84d801fae5c268c |
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