Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite

Abstract A robust nanobiocomposite based on core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons (MWCNTs@rGONRs)/chitosan (CHIT) was described for the fabrication of sensitive, selective, reproducible and durable biosensor for hydrogen peroxide (H2O2) and nitri...

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Autores principales:	Veerappan Mani, Mani Govindasamy, Shen-Ming Chen, Tse-Wei Chen, Annamalai Senthil Kumar, Sheng-Tung Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/14a4ea8edbc2402aa9058014e3b49881
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spelling	oai:doaj.org-article:14a4ea8edbc2402aa9058014e3b498812021-12-02T15:06:08ZCore-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite10.1038/s41598-017-12050-x2045-2322https://doaj.org/article/14a4ea8edbc2402aa9058014e3b498812017-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-12050-xhttps://doaj.org/toc/2045-2322Abstract A robust nanobiocomposite based on core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons (MWCNTs@rGONRs)/chitosan (CHIT) was described for the fabrication of sensitive, selective, reproducible and durable biosensor for hydrogen peroxide (H2O2) and nitrite (NO2 −). The excellent physicochemical properties of MWCNTs@rGONRs such as, presence of abundant oxygen functionalities, higher area-normalized edge-plane structures and chemically active sites in combination with excellent biocompatibility of CHIT resulting in the versatile immobilization matrix for myoglobin (Mb). The most attractive property of MWCNTs@rGONRs which distinguishes it from other members of graphene family is its rich edge density and edge defects that are highly beneficial for constructing enzymatic biosensors. The direct electron transfer characteristics such as, redox properties, amount of immobilized active Mb, electron transfer efficiency and durability were studied. Being as good immobilization matrix, MWCNTs@rGONRs/CHIT is also an excellent signal amplifier which helped in achieving low detection limits to quantify H2O2 (1 nM) and NO2 − (10 nM). The practical feasibility of the biosensor was successfully validated in contact lens cleaning solution and meat sample.Veerappan ManiMani GovindasamyShen-Ming ChenTse-Wei ChenAnnamalai Senthil KumarSheng-Tung HuangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Veerappan Mani Mani Govindasamy Shen-Ming Chen Tse-Wei Chen Annamalai Senthil Kumar Sheng-Tung Huang Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite
description	Abstract A robust nanobiocomposite based on core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons (MWCNTs@rGONRs)/chitosan (CHIT) was described for the fabrication of sensitive, selective, reproducible and durable biosensor for hydrogen peroxide (H2O2) and nitrite (NO2 −). The excellent physicochemical properties of MWCNTs@rGONRs such as, presence of abundant oxygen functionalities, higher area-normalized edge-plane structures and chemically active sites in combination with excellent biocompatibility of CHIT resulting in the versatile immobilization matrix for myoglobin (Mb). The most attractive property of MWCNTs@rGONRs which distinguishes it from other members of graphene family is its rich edge density and edge defects that are highly beneficial for constructing enzymatic biosensors. The direct electron transfer characteristics such as, redox properties, amount of immobilized active Mb, electron transfer efficiency and durability were studied. Being as good immobilization matrix, MWCNTs@rGONRs/CHIT is also an excellent signal amplifier which helped in achieving low detection limits to quantify H2O2 (1 nM) and NO2 − (10 nM). The practical feasibility of the biosensor was successfully validated in contact lens cleaning solution and meat sample.
format	article
author	Veerappan Mani Mani Govindasamy Shen-Ming Chen Tse-Wei Chen Annamalai Senthil Kumar Sheng-Tung Huang
author_facet	Veerappan Mani Mani Govindasamy Shen-Ming Chen Tse-Wei Chen Annamalai Senthil Kumar Sheng-Tung Huang
author_sort	Veerappan Mani
title	Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite
title_short	Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite
title_full	Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite
title_fullStr	Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite
title_full_unstemmed	Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite
title_sort	core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/14a4ea8edbc2402aa9058014e3b49881
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Core-shell heterostructured multiwalled carbon nanotubes@reduced graphene oxide nanoribbons/chitosan, a robust nanobiocomposite for enzymatic biosensing of hydrogen peroxide and nitrite

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