A screen for inhibitory peptides of hepatitis C virus identifies a novel entry inhibitor targeting E1 and E2

Abstract Hepatitis C virus (HCV) entry into hepatocytes is a multistep process that represents a promising target for antiviral intervention. The viral envelope protein E1E2 plays a critical role in HCV entry. In this study, we sought to identify peptide inhibitors of HCV by screening a library of o...

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Autores principales: Peiqi Yin, Ling Zhang, Fei Ye, Yao Deng, Sha Lu, Yi-Ping Li, Leiliang Zhang, Wenjie Tan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/14a535e894574041ba6a7a01d70ccb93
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