Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor

Long Non-coding RNA Uc.48+ Small Interfering RNA Alleviates Neuroinflammatory Hyperalgesia in Gp120-Treated Rats via the P2Y12 Receptor

Human immunodeficiency virus envelope glycoprotein 120 (gp120) leads to hyperalgesia. Long non-coding RNAs are characterized by the lack of a protein-coding sequence and may contribute to the development and maintenance of inflammatory and neuroinflammatory pain. Rats with neuroinflammatory pain wer...

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Bibliographic Details
Main Authors: Lichao Peng, Bing Wu, Liran Shi, Lifang Zou, Lin Li, Runan Yang, Xiumei Xu, Guilin Li, Shuangmei Liu, Chunping Zhang, Shangdong Liang
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
dorsal root ganglia
HIV gp120-associated neuroinflammatory pain
long non-coding RNA
small interfering RNA
P2Y12 receptor
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Online Access:https://doaj.org/article/14a58a6433434ac39fedc2ffeb47e42a
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https://doaj.org/article/14a58a6433434ac39fedc2ffeb47e42a

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