Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae

Antimicrobial resistance is a global health challenge. Few new antibiotics have been developed for use over the years, and preserving the efficacy of existing compounds is an important step to protect public health. This paper describes a study that examines the effects of exogenously induced oxid...

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Autores principales: João Anes, Katherine Dever, Athmanya Eshwar, Scott Nguyen, Yu Cao, Sathesh K. Sivasankaran, Sandra Sakalauskaitė, Angelika Lehner, Stéphanie Devineau, Rimantas Daugelavičius, Roger Stephan, Séamus Fanning, Shabarinath Srikumar
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/14a94f637a5743119c7891bd75fb49a9
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Sumario:Antimicrobial resistance is a global health challenge. Few new antibiotics have been developed for use over the years, and preserving the efficacy of existing compounds is an important step to protect public health. This paper describes a study that examines the effects of exogenously induced oxidative stress on K. pneumoniae