Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
Pulmonary infections constitute a substantial health problem worldwide. Here the authors show that phagocytes similar to primitive macrophages can be generated from human induced pluripotent stem cells, by the use of industry-compatible, stirred-tank bioreactors, and applied as a cell-based therapy...
Saved in:
Main Authors: | Mania Ackermann, Henning Kempf, Miriam Hetzel, Christina Hesse, Anna Rafiei Hashtchin, Kerstin Brinkert, Juliane Wilhelmine Schott, Kathrin Haake, Mark Philipp Kühnel, Silke Glage, Constanca Figueiredo, Danny Jonigk, Katherina Sewald, Axel Schambach, Sabine Wronski, Thomas Moritz, Ulrich Martin, Robert Zweigerdt, Antje Munder, Nico Lachmann |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/14b2e8c926bf42f1a34ca9cec6a3b9d0 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The CpG-sites of the CBX3 ubiquitous chromatin opening element are critical structural determinants for the anti-silencing function
by: Jessica Kunkiel, et al.
Published: (2017) -
Estimation of Volumetric Mass Transfer Coefficient in Bioreactor
by: Zainab Yaquob Atiya
Published: (2012) -
Estimation of Volumetric Mass Transfer Coefficient in Bioreactor
by: Zainab Yaquob Atiya
Published: (2012) -
Anaerobic membrane bioreactors: Are membranes really necessary?
by: Jeison,David, et al.
Published: (2008) -
Treatment of seawater salinity sewage with intermittent sand bioreactors
by: Kristen M. Conroy, et al.
Published: (2021)