Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo

The development of vaccines against infectious diseases has helped us battle the greatest threat to public health. With the emergence of novel viruses, targeted immunotherapeutics ranging from informed vaccine development to personalized medicine may be the very thing that separates us between life...

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Autores principales:	Ruby A. Escobedo, Dhiraj K. Singh, Deepak Kaushal
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	COVID-19 2019-nCoV SARS-CoV-2 Coronavirus beta-coronavirus vaccine development Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/14b4f4b43c02401d87012fb0ce747a4a
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spelling	oai:doaj.org-article:14b4f4b43c02401d87012fb0ce747a4a2021-11-11T08:36:51ZUnderstanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo1664-322410.3389/fimmu.2021.765349https://doaj.org/article/14b4f4b43c02401d87012fb0ce747a4a2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.765349/fullhttps://doaj.org/toc/1664-3224The development of vaccines against infectious diseases has helped us battle the greatest threat to public health. With the emergence of novel viruses, targeted immunotherapeutics ranging from informed vaccine development to personalized medicine may be the very thing that separates us between life and death. Late in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), made a remarkable entrance to human civilization, being one of many to cross the species barrier. This review discusses the important aspects of COVID-19, providing a brief overview of our current understanding of dysregulated immune responses developed using various experimental models, a brief outline of experimental models of COVID-19 and more importantly, the rapid development of vaccines against COVID-19.Ruby A. EscobedoRuby A. EscobedoDhiraj K. SinghDeepak KaushalFrontiers Media S.A.articleCOVID-192019-nCoVSARS-CoV-2Coronavirusbeta-coronavirusvaccine developmentImmunologic diseases. AllergyRC581-607ENFrontiers in Immunology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 2019-nCoV SARS-CoV-2 Coronavirus beta-coronavirus vaccine development Immunologic diseases. Allergy RC581-607
spellingShingle	COVID-19 2019-nCoV SARS-CoV-2 Coronavirus beta-coronavirus vaccine development Immunologic diseases. Allergy RC581-607 Ruby A. Escobedo Ruby A. Escobedo Dhiraj K. Singh Deepak Kaushal Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo
description	The development of vaccines against infectious diseases has helped us battle the greatest threat to public health. With the emergence of novel viruses, targeted immunotherapeutics ranging from informed vaccine development to personalized medicine may be the very thing that separates us between life and death. Late in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), made a remarkable entrance to human civilization, being one of many to cross the species barrier. This review discusses the important aspects of COVID-19, providing a brief overview of our current understanding of dysregulated immune responses developed using various experimental models, a brief outline of experimental models of COVID-19 and more importantly, the rapid development of vaccines against COVID-19.
format	article
author	Ruby A. Escobedo Ruby A. Escobedo Dhiraj K. Singh Deepak Kaushal
author_facet	Ruby A. Escobedo Ruby A. Escobedo Dhiraj K. Singh Deepak Kaushal
author_sort	Ruby A. Escobedo
title	Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo
title_short	Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo
title_full	Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo
title_fullStr	Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo
title_full_unstemmed	Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo
title_sort	understanding covid-19: from dysregulated immunity to vaccination status quo
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/14b4f4b43c02401d87012fb0ce747a4a
work_keys_str_mv	AT rubyaescobedo understandingcovid19fromdysregulatedimmunitytovaccinationstatusquo AT rubyaescobedo understandingcovid19fromdysregulatedimmunitytovaccinationstatusquo AT dhirajksingh understandingcovid19fromdysregulatedimmunitytovaccinationstatusquo AT deepakkaushal understandingcovid19fromdysregulatedimmunitytovaccinationstatusquo
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Understanding COVID-19: From Dysregulated Immunity to Vaccination Status Quo

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