TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression

TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression

Insulin resistance is associated with development of type 2 diabetes. Here the authors show that TAZ interacts with c-Jun and Tead4, inducing expression of the insulin receptor substrate 1 (IRS1) leading to increased glucose uptake in muscle, and that its activity is counteracted by statin administr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jun-Ha Hwang, A Rum Kim, Kyung Min Kim, Jung Il Park, Ho Taek Oh, Sung A Moon, Mi Ran Byun, Hana Jeong, Hyo Kyung Kim, Michael B. Yaffe, Eun Sook Hwang, Jeong-Ho Hong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/14b73c8beec04ed68f0d0254de686c27
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares