Protective effect of the HLA-DRB1*13:02 allele in Japanese rheumatoid arthritis patients.

Protective effect of the HLA-DRB1*13:02 allele in Japanese rheumatoid arthritis patients.

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease. Certain HLA-DRB1 "shared-epitope" alleles are reported to be positively associated with increased RA susceptibility, whereas some of the other alleles may be negatively associated. However, studies on the latter are rare...

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Autores principales: Shomi Oka, Hiroshi Furukawa, Aya Kawasaki, Kota Shimada, Shoji Sugii, Atsushi Hashimoto, Akiko Komiya, Naoshi Fukui, Satoshi Ito, Tadashi Nakamura, Koichiro Saisho, Masao Katayama, Shinichiro Tsunoda, Hajime Sano, Kiyoshi Migita, Akiko Suda, Shouhei Nagaoka, Naoyuki Tsuchiya, Shigeto Tohma
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/14bced75e3a94961b82be185c94b0c68
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